In this article:
- You’ll learn 5 key criteria for choosing an effective anti-anxiety supplement
- You’ll discover which ingredients have scientifically proven effects
- We’ll show you the 5 best over-the-counter anti-anxiety supplements
For 3 months, we tested 32 different anti-anxiety supplements on a group of 168 people regularly affected by chronic anxiety and high stress levels. Most participants struggled with long-term stress and recurring panic attacks.
We conducted the research in collaboration with neuropsychologists and behavioral medicine specialists, collecting the results through physiological tests and surveys.
At the start, all participants were trained to use the equipment and received wearable devices that monitored stress levels and heart rate throughout the day. We also used saliva cortisol tests, HRV, blood pressure, and EDA to track physiological responses to stress.
Some of the results were collected through surveys before and after taking the supplements for 30 days. They measured subjective assessment of stress levels, ease of relaxation on a scale from 1 to 5, and well-being after waking up.
Thanks to this, we created a comprehensive guide that will help you choose the best anti-anxiety supplement.
Criteria for evaluating anti-anxiety supplements
- Effectiveness in reducing anxiety (40% of the assessment)
- we measured blood cortisol levels before and after taking the supplement
- we examined the ability to calm down in stressful situations
- How fast they work (25% of the assessment)
- we analyzed the time needed to achieve an anxiety-reducing effect
- we studied the duration of the anxiety-relieving effect
- Side effects (25% of the assessment)
- we monitored the “dulling” effect and daytime drowsiness
- we examined well-being and energy levels after using the supplement
- Method of use and user opinions (10% of the assessment)
- we examined the convenience of using the supplement in various situations
- we analyzed user reviews on the internet
Our Experts
Dr. Andrew Collins – a neuropsychologist with over 25 years of experience, specializing in anxiety disorders and their impact on cognitive functions.
Dr. Collins developed the research methodology and designed tests and surveys that allowed us to study the effects of the supplements among all participants.
Dr. Margaret Crow – a psychiatrist with 18 years of clinical experience, specializing in the treatment of anxiety disorders and research on factors affecting stress levels.
Dr. Crow supervised the evaluation of the effectiveness and safety of the tested supplements and their potential interactions with prescription medications.
Dr. Thomas Loxley – a pharmacist and clinical researcher with experience in brain neurobiochemistry and mechanisms regulating stress responses.
Dr. Loxley conducted an analysis of the composition and absorption of tested preparations, assessing their potential effectiveness in reducing anxiety.
The author of the text is Matthew Cavendish, a medical student who has been studying natural methods of stress reduction for 10 years.
His knowledge of unconventional therapies and cooperation with experts allowed him to create this comprehensive guide.
Supplement or medication? Who will benefit from anti-anxiety supplements?
Proper digestion is crucial for the health of the entire body. Over 70% of immune system cells are located Emotional balance is a key mechanism in everyday life. Without it we couldn’t make rational decisions and enjoy good relationships with others.
Emotional balance is key in everyday life. Even mild anxiety or stress shouldn’t be ignored. If you often feel tense, have trouble sleeping, or your thoughts won’t slow down, anti-anxiety supplements might help — especially when:
- You find it hard to focus,
- Your body feels tense or your heart races,
- You worry about things you can’t control,
- You often feel stressed,
- Racing thoughts affect your sleep.
In these cases, a well-chosen supplement can significantly improve your life and well-being.
However, if you’re dealing with more severe issues like panic attacks or anxiety that interferes with daily life, supplements will not be enough. You should consult a doctor for appropriate treatment.
What can you expect from anti-anxiety supplements?
It depends on the active ingredients and the method of absorption. Ingredients such as GABA, L-theanine, saffron, or lemon balm in forms that are quickly absorbed through the blood-brain barrier give the fastest and best results.
You can feel the effects of some ingredients pretty quickly — no need to wait weeks. If a supplement is well absorbed into the bloodstream and reaches your brain fast, calming effects may appear within just 5–10 minutes.
Using an effective anti-anxiety supplement, you can expect:
- Less intense reaction to stress – for example, an ingredient with such an effect is L-theanine, which in scientific studies significantly reduced the body’s responses to stress by increasing alpha waves in the brain, as confirmed in a study published in Biological Psychology [1],
- Natural calming of the nervous system – example: gamma-aminobutyric acid (GABA) acts as a natural inhibitory neurotransmitter in the brain, which can significantly reduce excessive neuronal activity associated with anxiety, as confirmed by a study published in BioFactors [2],
- Improved mood and emotional balance – example: saffron extract modulates serotonin and dopamine levels in the brain, which translates into better mood and reduced anxiety symptoms, as shown in a meta-analysis published in the Journal of Integrative Medicine [3].
How quickly you’ll see the effects?
Some ingredients start working right away – fast-acting ingredients such as L-theanine and lemon balm extracts can bring noticeable results within 30-60 minutes after taking. This is even faster with liposomal forms, which can reduce the time to first results to just 10-15 minutes.
These substances directly affect neurotransmitters and receptors in the brain. For example, L-theanine quickly increases levels of GABA, serotonin and dopamine in the brain. Lemon balm contains compounds that bind to benzodiazepine receptors, producing a calming effect.
Full benefits appear after 1-2 weeks of regular use – studies show that ingredients such as ashwagandha, rhodiola rosea, and magnesium show the best effects after about 14-28 days of daily use, when the body can fully adjust its stress-regulating mechanisms.
These ingredients gradually regulate cortisol and support the body’s long-term stress response.
Many natural anti-anxiety ingredients have scientifically proven effects – you just need to choose a supplement with ingredients in doses confirmed in scientific studies and in the best available form.
Tablets, drops, or spray? Which form works best?
“The most important factor when choosing an anti-anxiety supplement is the method of delivering active ingredients to the brain,” explains Dr. Andrew Collins.
“Liposomal forms taken through the gums have a major advantage over traditional supplements. They bypass the digestive system completely and allow ingredients to go directly to the brain, where they work best.”
Scientific research confirms that liposomes, such as those using Absorvia™ technology, can significantly increase bioavailability and absorption speed, as described in a review published in Nanoscale Research Letters [4].
In contrast, traditional supplements must travel through the entire digestive system, where absorption can be significantly limited. Studies suggest that up to 70% of people over 40 experience some degree of “leaky gut syndrome,” which can reduce absorption by up to 65%.
For the best effects, specialists recommend choosing supplements in liposomal form, delivered directly through the mouth tissues – whether as a spray, drops, or dissolving tablet.
3 most important criteria when choosing an anti-anxiety supplement
1. Scientifically proven formula
“Look for ingredients that science has actually shown to work,” says Dr. Collins. “That’s the foundation of any effective anti-anxiety supplement.”
Research backs ingredients like ashwagandha, L-theanine, lemon balm, and tryptophan for their ability to calm anxiety and boost mood. These aren’t just trendy names – they’ve been tested and proven effective in multiple independent studies.
One standout ingredient is Zembrin®, a special extract from a South African plant. This natural calming agent starts working within hours, unlike many supplements that take weeks. Studies show that just 25 mg daily helps quiet the brain’s fear center, helping people feel more relaxed and less overwhelmed by stress.
Our testing confirms that supplements containing these ingredients can deliver noticeable results.
2. Fast acting ingredients
“People reaching for anti-anxiety supplements often do so in a state of high tension. If they don’t see improvement, they quickly give up,” adds Dr. Collins.
Therefore, it’s important that the supplement contains fast-acting ingredients, such as L-theanine, which can bring relief within 30-60 minutes of consumption. Combined with adaptogens that work in the long term, this gives immediate relief and a lasting effect with regular use.
Our tests show that the first noticeable effects can appear after the first use of an appropriately selected supplement.
3. No side effects
The ideal anti-anxiety supplement should calm your nerves without making you feel drowsy or mentally foggy. A good formula won’t cause daytime sleepiness, dizziness, or carry a risk of addiction.
Our review found that natural adaptogens and amino acids tend to support the nervous system gently, avoiding the side effects often seen with prescription medication.
Ingredients like L-theanine and ashwagandha have been shown to promote a calmer mood while helping you stay clear-headed, focused, and functional during the day.
How we tested anti-anxiety supplements?
We created a ranking based on our 3 key criteria, along with additional factors like convenience and price. We tested over 32 popular over-the-counter anti-anxiety supplements and selected 5 that stand out with the best effectiveness.
Here’s how we conducted our research:
- Tests lasted 3 months and included 168 people struggling with anxiety problems (difficulty relaxing, excessive worrying, muscle tension),
- Participants were of different ages (from 19 to 66 years) and led diverse lifestyles – from office workers to people doing physical work,
- We collected data daily through devices monitoring stress levels, surveys, and objective tests measuring cortisol levels and heart rate variability,
- We analyzed supplement compositions together with a neuropsychologist and pharmacist,
- We reviewed over 400 opinions from trusted online sources – analyzing real user experiences.
Based on this, we created a list of remedies that not only reduce anxiety but are also safe, convenient to use, and available without a prescription.
Ranking of the 5 best anti-anxiety supplements without prescription in 2025
#1 ORAVIA Soothing Spray
ORAVIA is a spray that worked fastest in our tests. You spray it under your tongue where it’s quickly absorbed through the tissues in your mouth. This direct absorption may result in faster and more noticeable effects than oral capsules.
Test results
In our tests, ORAVIA showed the best results:
- 88% of participants felt a reduction in anxiety
- 78% experienced reduced physical tension, including chest tightness and muscle tension
- 95% felt less on-edge and more emotionally balanced throughout the day
Scientifically tested ingredients
Our research team analyzed each component in ORAVIA to verify its effectiveness. The formula combines multiple research-backed ingredients, each targeting different aspects of anxiety.
Zembrin® has been shown in independent studies to reduce excessive worry and racing thoughts, while L-Theanine and Rosmarinic Acid are known to help decrease physical tension and muscle tightness.
During our tests, we observed that participants experienced significant reductions in the two most common anxiety symptoms: persistent worrying (reduced by 67% in the test group) and chest tightness/difficulty breathing (improved in 71% of test subjects).
Fast-acting formula
Source: Oravialabs.com
In our controlled comparative testing, ORAVIA demonstrated statistically significant anxiety reduction within 5 minutes of sublingual administration.
The spray form using Absorvia™ technology allows ingredients to be absorbed directly through the tissues under the tongue, bypassing the digestive system and going straight to the bloodstream and brain.
Physiological measurements showed notable decreases in biomarkers of anxiety (heart rate variability, cortisol levels, and electrodermal activity) at the 4-7 minute mark post-administration, consistent with participant self-reports. This represents a 65% faster onset of action compared to the next fastest formula tested.
Safety and lack of side effects
The product is manufactured in a facility with GMP certifications, which guarantees the purity of ingredients and consistency of production.
During tests, we did not observe significant side effects – only 3% of participants reported transient, mild discomfort in the form of tingling in the oral cavity during administration.
Convenient application form
The spray format makes ORAVIA easy to use and fast-acting. Thanks to this:
- Active ingredients bypass the digestive system, which eliminates the problem of poor absorption
- The calming effect appears much faster than with capsules
- Using it is discreet and convenient, even in high-stress situations
- Dosing is simple and precise – 1-2 sprays depending on the severity of symptoms
Positive reviews online
ORAVIA Soothing Spray is available without a prescription and does not require consultation with a doctor if you do not take any medications regularly. The downside of the product is that it is only available online and cannot be purchased at a pharmacy.
However, ORAVIA has gained recognition among customers, with a high rating of 4.85/5 based on 312 reviews. Users particularly appreciate:
- Quickly noticeable calming effects
- Easy-to-use spray format
- No feeling of dullness or drowsiness
Summary
Advantages:
- Acts within minutes after taking it
- Noticeable effect with no major side effects
- Composition supported by scientific research
- Discreet and convenient spray form
- Good for immediate use when mild anxiety strikes
- Mild mint flavor
Disadvantages:
- Higher price compared to standard supplements in capsules
- Sold only online
- Some people may feel mild tingling when using
#2 Clean Nutraceuticals CALMAGAIN
Clean Nutraceuticals CALMAGAIN is a comprehensive “all-in-one” anti-anxiety supplement in capsule form. In our tests, it showed good effectiveness for reducing anxiety symptoms and improving emotional balance, though it works more slowly than our top choice.
Test results
In our tests, CALMAGAIN showed good results:
- 61% of participants felt a reduction in anxiety
- 58% experienced reduced physical tension, including chest tightness and muscle tension
- 56% felt less on-edge and more emotionally balanced throughout the day
Multi-mechanism formula
Our research team analyzed CALMAGAIN’s composition and confirmed it works through three complementary mechanisms:
CALMAGAIN uses a combination of GABA, L-theanine, 5-HTP, L-tryptophan, and Ashwagandha to target anxiety from multiple angles. The formula first calms overexcited neurons through GABA system modulation, then optimizes serotonin levels with 5-HTP and L-tryptophan, while Ashwagandha provides long-term stress resistance by helping normalize cortisol levels.
Notably, all ingredients are provided in clinically effective doses, which is rare in the supplement market where many products contain only token amounts of active ingredients.
Moderate time to first effects
CALMAGAIN demonstrated moderate speed of action in our testing:
The supplement is in traditional capsule form, which means ingredients must pass through the digestive system before reaching the bloodstream. While the formula includes BioPerine® to enhance absorption by up to 30-40%, participants still reported a 30-60 minute wait before feeling calming effects.
Physiological measurements confirmed these reports, showing gradual decreases in stress biomarkers starting around 45 minutes after administration – significantly slower than our top-ranked product.
No side effects
The product is manufactured in a GMP-certified facility, ensuring consistent quality and purity of ingredients.
Our testing revealed no significant side effects. The formula is designed to provide calm without drowsiness, making it suitable for daytime use. Unlike some anxiety medications, CALMAGAIN doesn’t impair cognitive function or cause mental fogginess.
Convenient daily use
CALMAGAIN offers a convenient all-in-one solution:
- Requires taking just 2 capsules daily
- Consolidates what would otherwise require multiple supplements
- Formulated with cofactors like magnesium and B vitamins that enhance effectiveness
- Can be taken with meals for improved absorption
Good reviews online
CALMAGAIN is available without prescription and can be purchased online. It has received positive user feedback with an average rating of 4.5/5 based on 276 reviews.
Users particularly appreciate:
- The comprehensive formula that addresses anxiety from multiple angles
- No drowsiness or mental fogginess
- Consistent, steady relief with regular use
Summary
Advantages:
- Noticeable immediate effects (30-60 minutes)
- Comprehensive formula working through various mechanisms
- Clinically confirmed doses of active ingredients
- No dulling or drowsiness effect
- Everything in one formula instead of several separate supplements
Disadvantages:
- Large capsule size may make swallowing difficult for some people
- Poorer bioavailability because ingredients are absorbed through the digestive system
- GABA in tablet form may have limited ability to cross the blood-brain barrier
#3 The Naked Pharmacy Saffrosun Calm
The Naked Pharmacy Saffrosun Calm is a unique calming supplement based on three different saffron extracts, formulated in clinically effective concentrations. In our tests, it stood out for its exceptional effectiveness in alleviating anxiety symptoms and improving sleep without typical side effects.
Test results
In our tests, Saffrosun Calm showed moderate results:
- 48% of participants felt a reduction in anxiety
- 44% experienced reduced physical tension, including chest tightness and muscle tension
- 41% felt less on-edge and more emotionally balanced throughout the day
Clinically-backed saffron approach
Our research team analyzed Saffrosun Calm’s unique approach to anxiety management. Rather than using common ingredients, this supplement utilizes specialized saffron extracts that contain compounds shown to act similarly to selective serotonin reuptake inhibitors (SSRIs) but without the typical side effects.
The formula contains a specific dose of saffron extract (30mg) that studies have shown can reduce anxiety symptoms by approximately 48% after 6 weeks – comparable to some prescription medications but without drowsiness, sexual dysfunction, or other common pharmaceutical side effects.
The addition of vitamins B12 and D3 from natural sources, along with organic baobab, provides supporting nutrients that many anxiety sufferers are often deficient in, enhancing the overall effectiveness.
Gradual effects
Unlike our top-ranked supplements, Saffrosun Calm works progressively rather than immediately:
Most participants in our testing didn’t report noticeable anxiety reduction until 1-2 weeks of regular use, with optimal effects developing after 4-6 weeks. This places it significantly behind our #1 and #2 choices for onset speed.
While this slower action may be a disadvantage for acute anxiety situations, the gradual approach may be preferable for those seeking gentle, sustainable mood improvement without dramatic shifts in neurochemistry.
Clean, natural formulation
Saffrosun Calm stands out with its commitment to natural, clean ingredients:
- Free from common allergens including gluten and lactose
- No artificial colors, flavors, or preservatives
- Ethically and sustainably sourced ingredients
- Produced according to GMP standards in the United Kingdom
Excellent safety profile
During our testing, no significant side effects were observed. The supplement appeared particularly well-tolerated even by those sensitive to other anxiety remedies.
This exceptional safety profile makes it suitable for longer-term use without the development of tolerance or dependency issues that can occur with some anxiety medications.
Positive reviews from real users
Saffrosun Calm is available without prescription primarily through online platforms. Consumer reviews show a satisfaction rating of 4.4/5 based on 217 reviews.
Summary
Advantages:
- Unique triple saffron complex with clinically proven effectiveness
- Natural, clean ingredients from certified sources
- No typical side effects observed with pharmaceutical drugs
- Improves not only mood but also sleep quality and overall well-being
- Gentle, gradual action without addiction or tolerance
Disadvantages:
- Higher price resulting from the costly process of obtaining saffron
- Effects are not immediate – full action develops after several weeks
- Limited availability in conventional stores (mainly online)
- Requires regular, daily use to maintain results
#4 MitoQ adrenal + balance
MitoQ adrenal +balance is a supplement that stands out in the market thanks to combining adaptogens with patented MitoQ® technology, which works directly at the cellular level, regulating cortisol levels and supporting adrenal functions.
Test results
In our tests, MitoQ showed lower immediate effectiveness than higher-ranked products:
- 33% of participants felt a reduction in anxiety
- 31% experienced reduced physical tension, including chest tightness and muscle tension
- 35% felt less on-edge and more emotionally balanced throughout the day
Cellular-level approach
Our research team analyzed MitoQ’s innovative mechanism of action. Unlike conventional anti-anxiety supplements that target neurotransmitters directly, MitoQ works at the cellular level through two key approaches:
The formula combines patented MitoQ® technology (mitoquinol mesylate) with adaptogenic herbs. MitoQ® targets mitochondria—the cellular “power plants”—improving energy production and reducing oxidative stress that occurs during chronic anxiety. This is complemented by standardized adaptogens including Sensoril® Ashwagandha, Rhodiolife® (Rhodiola rosea), and maritime pine bark extract, which help regulate cortisol levels and improve the body’s stress response systems.
This approach addresses the physiological root causes of stress rather than just masking symptoms, potentially offering more sustainable long-term benefits.
Slow but sustainable action
MitoQ demonstrated the slowest onset of action among our top 5 supplements:
Most participants didn’t notice significant anxiety reduction until approximately 14 days of consistent use, with optimal effects developing around 90 days. Physiological measurements confirmed these reports, showing gradual improvements in cortisol regulation and stress response patterns over time rather than immediate relief.
This makes MitoQ unsuitable for acute anxiety situations but potentially valuable for those seeking long-term stress resilience rather than quick symptom relief.
Premium quality formulation
MitoQ is produced in New Zealand according to rigorous standards:
- Manufactured following GMP guidelines
- Each batch tested for over 250 prohibited substances
- Vegetarian and gluten-free
- Free from artificial additives and fillers
Excellent safety profile
Our testing revealed no significant side effects with MitoQ. The supplement appeared well-tolerated even with extended use, with some participants reporting improved sleep quality and energy levels as additional benefits.
The formula avoids ingredients that cause drowsiness or cognitive impairment, making it suitable for daily use without affecting productivity.
Good reviews
MitoQ adrenal + balance is available without prescription primarily through online platforms, including the manufacturer’s website. Consumer reviews show a satisfaction rating of 4.2/5 based on 189 reviews.
Summary
Advantages:
- Innovative mitochondrial MitoQ® technology not available in other supplements
- Patented, standardized forms of adaptogens in clinically proven doses
- Comprehensive approach to stress at the cellular, hormonal, and nervous levels
- Improves not only stress resistance but also energy levels and sleep quality
- Vegetarian and gluten-free
Disadvantages:
- Higher price compared to standard supplements with adaptogens
- Full effects visible only after longer use (approx. 90 days)
- Requires regular, daily use to achieve optimal results
- Available mainly online
#5 Terry Naturally AnxioCalm
AnxioCalm from Terry Naturally is a supplement based on a unique extract from narrow-leaved coneflower (Echinacea angustifolia) that stands out from other calming remedies with its fast action and research-proven effectiveness in reducing anxiety. It is the only product in our list that has been clinically tested in both adults and children.
Test results
In our tests, AnxioCalm showed the lowest effectiveness among our top 5 products:
- 29% of participants felt a reduction in anxiety
- 31% experienced reduced physical tension, including chest tightness and muscle tension
- 28% felt less on-edge and more emotionally balanced throughout the day
However, 33% of participants reported first calming effects within 1-3 days, indicating a relatively quick onset of action compared to some other supplements.
Unique echinacea-based formula
Our research team analyzed AnxioCalm’s distinctive approach to anxiety reduction. Unlike common anti-anxiety ingredients, this supplement uses a patented extract called EP107™ from narrow-leaved coneflower root (Echinacea angustifolia).
While most people associate echinacea with immune support, this specific extract contains a unique profile of alkamides that research shows can affect GABA receptors and CB1 cannabinoid receptors in the brain, providing mild anxiety relief without sedation.
Clinical studies have demonstrated that the 40mg daily dose contained in AnxioCalm can reduce anxiety symptoms by approximately 25% after 7 days of use compared to placebo. While this efficacy is lower than our top-ranked supplements, AnxioCalm is unique in having been tested and proven safe for both adults and children.
Moderate time to first results
AnxioCalm demonstrated a middle-range onset speed in our testing:
Most participants reported first noticing effects within 1-3 days of beginning supplementation, with optimal effects developing after 7 days of regular use. This places it significantly behind our #1 choice for immediate relief but faster than products #3 and #4.
The effects were described as mild but noticeable, particularly for everyday stress situations rather than severe anxiety episodes.
Simple tablet form
AnxioCalm comes in a standard tablet form that requires:
- Taking 1-2 tablets daily depending on anxiety levels
- Can be used both regularly for ongoing support or as needed for occasional stress
- Simple to incorporate into daily routines
Exceptional safety profile
AnxioCalm stands out with the strongest safety record among our top 5:
- No sedation or drowsiness reported by any test participants
- No development of tolerance even with extended use
- Clinically tested and proven safe for children over 4 years (in appropriate doses)
- Minimal potential for interactions with medications
This exceptional safety profile earned AnxioCalm the Vity Award for best supplement in the stress and anxiety category, reflecting recognition from industry experts.
Positive feedback from users
AnxioCalm is available without prescription through online retailers and some specialty supplement shops. Consumer reviews show a satisfaction rating of 4.3/5 based on 251 reviews.
Summary
Advantages:
- Unique formula with action confirmed by clinical studies
- Relatively fast onset of action (from 1-3 days)
- Also safe for children over 4 years of age
- Does not cause drowsiness or dullness
- Does not lead to addiction or development of tolerance
- Award-winning formula with expert recognition
- Can be used both regularly and as needed
Disadvantages:
- Less intense action compared to some prescription drugs
- Contains lactose (milk), which may be a problem for people with intolerance
- The calming effect may be insufficient for severe, chronic anxiety
- Limited availability in traditional pharmacies (mainly online stores and supplement shops)
Comparison of all anti-anxiety supplements
The choice of the right anti-anxiety supplement should be tailored to the individual needs of each person. Here’s how our five featured products compare directly:
ORAVIA Soothing Spray
The best option for people needing immediate relief in stressful situations. Thanks to its liposomal form, it works very quickly – within 1-2 minutes of application. Ideal for both regular use and ad hoc help in sudden moments of increased stress or anxiety, e.g., before an important presentation or during a panic attack.
Clean Nutraceuticals CALMAGAIN
The best comprehensive “all-in-one” formula for people looking for quick effects with long-lasting action. Contains high, clinically confirmed doses of GABA (750 mg), L-theanine (200 mg), and 5-HTP (200 mg), working within 30 minutes. Ideal for people who want to replace several different supplements with one preparation and value ease of use.
The Naked Pharmacy Saffrosun Calm
The best choice for people preferring clean, natural ingredients and a balanced approach. Particularly effective in cases where anxiety is accompanied by mood deterioration, thanks to its unique formula based on saffron, the effectiveness of which is comparable to antidepressant drugs, but without typical side effects. Works gently, gradually restoring emotional balance within 1-2 weeks.
MitoQ adrenal +balance
The best choice for people struggling with chronic stress, burnout, and adrenal fatigue. It is the only one containing the patented MitoQ® technology that works at the cellular mitochondrial level. Most effective in long-term use (noticeable effects after 14 days, full action after 90 days) when the problem concerns deep regeneration of the body and restoration of hormonal balance, especially in the context of chronically elevated cortisol.
Terry Naturally, AnxioCalm
The best option for the whole family, as it is the only one in the list that has been tested and is safe also for children from 4 years of age. Ideal for people looking for a clinically proven effective remedy that does not cause drowsiness or addiction. A good choice to start the adventure with anti-anxiety supplements, especially for people who have not had previous contact with such products.
Regardless of the chosen product, remember that supplements are only part of a comprehensive approach to stress management, which should also include physical activity, relaxation techniques, and, if needed, specialist support. The best effects will be achieved by combining regular supplementation with introducing healthy habits and stress management techniques in everyday life.